Which side effect is associated with chlorpromazine?

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Prepare for the Dr. High Yield Psychiatry Test. Study with flashcards and multiple choice questions, each with hints and explanations. Ensure success in your exam!

Multiple Choice

Which side effect is associated with chlorpromazine?

Explanation:
This question tests a distinctive ocular side effect of chlorpromazine, a phenothiazine-type antipsychotic. Long-term use of this drug can lead to deposition of the medication in ocular tissues, most notably in the cornea. These corneal deposits appear as fine, often brownish opacities on slit-lamp examination and are a classic, well-described finding with chlorpromazine (and to a lesser extent with other phenothiazines). They’re not tied to kidney injury, hair loss, or metabolic disturbances like hyperglycemia, which makes corneal deposits the best match for the drug’s characteristic adverse effect.

This question tests a distinctive ocular side effect of chlorpromazine, a phenothiazine-type antipsychotic. Long-term use of this drug can lead to deposition of the medication in ocular tissues, most notably in the cornea. These corneal deposits appear as fine, often brownish opacities on slit-lamp examination and are a classic, well-described finding with chlorpromazine (and to a lesser extent with other phenothiazines). They’re not tied to kidney injury, hair loss, or metabolic disturbances like hyperglycemia, which makes corneal deposits the best match for the drug’s characteristic adverse effect.

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