Which of the following is a contraindication to bupropion?

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Multiple Choice

Which of the following is a contraindication to bupropion?

Explanation:
Bupropion lowers the seizure threshold, so a history of seizures is a major reason not to use it. That risk makes seizure disorder the strongest contraindication among the options. In practice, an eating disorder can also raise seizure risk due to electrolyte disturbances, so it’s another important caution, but the classic absolute contraindication to avoid based on the listed choices is a seizure disorder. Hypertension and hyperlipidemia don’t by themselves stop bupropion use, though high or unstable blood pressure should be monitored.

Bupropion lowers the seizure threshold, so a history of seizures is a major reason not to use it. That risk makes seizure disorder the strongest contraindication among the options. In practice, an eating disorder can also raise seizure risk due to electrolyte disturbances, so it’s another important caution, but the classic absolute contraindication to avoid based on the listed choices is a seizure disorder. Hypertension and hyperlipidemia don’t by themselves stop bupropion use, though high or unstable blood pressure should be monitored.

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